PSY 214 Lecture Notes - Lecture 2: Drug Metabolism, Psychoactive Drug, Abdominal Wall
Document Summary
Pharmacokinetics is the study of how an organism affects a drug, whereas pharmacodynamics is the study of how the drug affects the organism pharmacokinetics. While in the blood, a drug may also bind to inactive sites such as plasma proteins or storage depots (bone or fat) inactivation: drug inactivation, or biotransformation, occurs primarily as a result of metabolic processes in the liver. The amount of drug in the body at any one time is dependent on the dynamic balance between absorption and inactivation. Therefore, inactivation influences both the intensity and duration of drug effects: excretion: the liver metabolites are eliminated from the body with the urine or feces. Some drugs are excreted in an unaltered form by the kidneys. intestines, kidneys, sweat glands (feces, urine, water vapor, sweat, saliva) routes of administration: oral: P. o. (per os)- used as an abbreviation for medication to be taken orally.
