BISC 101 Lecture Notes - Lecture 19: Adrenal Medulla, Adrenal Cortex, Endocrine System

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Endocrine signals: are hormones carried between cells by blood or other body fluids. Neuroendocrine signals (system): released from neurons into circulation and act on distant cells only affecting target cells expressing specific receptors for that hormone. Hormones signalling acts through three pathways and is regulated by negative feedback. Endocrine pathway: hormone released by non-neural (glandular) endocrine cell into circulation. Neuroendocrine pathway: neurohormone from modified nerve cell (neurosecretory cell) directly affects target cell. Hormone: organic chemical messenger; at low concentrations; generally have long lasting effects. Synthesized/secreted by glandular (endocrine) and neurosecretory (neuroendocrine) cells. Transported in circulation and have action on distant target cell/tissue. Only affect target cells with specific receptors. Lipid solubility: determines whether hormone passes easily through plasma membrane to target/effector cell. Anterior pituitary:hypothalamus and pituitary work together to regulate: short axon neurosecretory cells originating in hypothalamus produce neurohormones, releasing- hormones rh, release-inhibiting hormones ih. Posterior pituitary: hypothalamus and pituitary work together to regulate: long axon neurosecretory.

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