BPK 205 Lecture Notes - Lecture 5: Phosphorylation, Irreversible Antagonist, Skeletal Muscle

• School: Simon Fraser University
• Department: Biomedical Physio & Kines
• Course: BPK 205
• Professor: Nadine Wicks

Document Summary

Classification of hormones: hormones may be classified based on, source -> ex. Pancreatic hormones: neuronal control of release, receptor type, chemical structure, function -> ex. Peptide/protein hormones: made in endocrine cells all over the body, made in advance and stored in vesicle for release, stored until needed, preprohormone -> prohormone -> hormone, large, inactive preprohormone made first. 2: lipophobic -> binds to membrane receptors, will not travel through the membrane, activates 2nd messenger system, response usually involves altered activity of target proteins. Intracellular receptors -> slow genomic response: modulation and regulation of gene activity, receptors in nucleus or cytoplasm, they are lipophilic so they can go through membranes, membrane receptors -> fast non-genomic response, less common than intracellular receptors. Amine hormones: made in pineal gland, adrenal medulla, thyroid, mostly derived from tyrosine, catecholamines (ex. Describe some endocrine organs and the hormones they produce. Endocrine vs exocrine secretions: gland = collection of secretory cells.