CRIM 101 Lecture Notes - Lecture 5: Bad Hindelang, Neurosis, The Kallikak Family

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Studying human genetics can be difficult from an ethical, numerical and biological perspective. Good scientific studies require a large number of identical research subjects. Cannot (ethically or legally) clone identical human beings for use as research subjects. Even large scale studies (drug trials) are influenced by biological factors and environmental factors (diet, lifestyle) Clones do exist, in the form of twins. Dizygotic (dz) twins result from 2 sperm fertilizing two eggs ( no more genetically similar than any other pair of full siblings ) Monozygotic (mz) twins result from single sperm fertilizing single egg, which then cleaves and becomes two separate zygotes ( two genetically identical babies ) Result from single sperm fertilizing egg (two genetically identical babies) Share 100% of the 1% of dna that explains variation in characteristics. Result from 2 sperm fertilizing two eggs (no more similar than any other siblings) Share 50% of the 1% dna that explains variation in characteristics.

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