Class Notes (808,107)
Canada (493,013)
HSCI 216 (49)


2 Pages
Unlock Document

Simon Fraser University
Health Sciences
HSCI 216
Pablo Nepomnaschy

HSCI216: LECTURE III May 16, 2012  Question Period st o Next week 1 draft of term paper, next Friday midterm (first 4 lectures) o Concepts are important, specific questions on point in video (because it relates to a concept) o Mutation rates: (question ppl have trouble with)  mutation rates vary across species, within species genome across regions and between DNA’s (nuclear vs mitochondrial)  By observing we know mutation rates are different  Why: accumulation (not the rate of mutation) is faster in “junk” DNA  Mutation rate: how quickly/often in each generation do we see mutations  when mutation occurs in “functional” piece of DNA  Accumulation: how many of those do we see across a piece of DNA  when mutation occurs in non-functional piece of DNA o This is how it is used as a clock ***  Places in the genome where mutation rate it hot/cold (fast/slow), there are places where the genome contains places that help the human body become more efficient (such as the immune system) o Mitochondrial DNA mutates faster than nuclear DNA  Why? Only empirically we know, possibly mitochondrial DNA has more junk? o Proximate explanation: how things happen? From a mechanism point of view  Ex: birds migrating  when days ge
More Less

Related notes for HSCI 216

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.