HSCI 211 Lecture Notes - Lecture 9: Framingham Risk Score, Polypill, Myocardial Infarction
Document Summary
Week 9 hsci 211 cardiovascular prevention & control: individual level. Interheart: summary: 9 simple risk factors strongly associated w/ acute mi worldwide, most important in young, effects consistent in m & w, in all ethnic groups, abnormal apo-b/apoa-1 ratio & smoking are most important risk factors. Implications: implementing preventive strategies based on current knowledge prevent premature heart attacks worldwide. Lipids & lipoproteins: lipids insoluble in h2o, travel through circulation in monolayered vesicles called lipoproteins. Abnormal blood lipids effects : relation b/w serum cholesterol & cvd, hdl & hdl-c are inversely related to coronary heart disease, reducing serum cholesterol reduces cvd, biological gradient of risk, no threshold level of low serum cholesterol. There are different guidelines for reducing a person"s cholesterol levels, according to level of risk. Incorporates age sex, lipids smoking status diabetes status. Use of generic drugs keep cost down. Ease of use by patient and improved adherence.
