HKIN 425 Lecture Notes - Lecture 18: Bone Resorption, Deconditioning, 3 Women
Document Summary
Positive: genetics, early onset of puberty (females, estrogen, hormonal status, estrogen and testosterone, nutrition, calories, ca++, vit d. Physical activity elevates serum testosterone and estrogen: weight bearing activities, strength building activities, early pa has lasting benefits. Negative: genetics, late onset of puberty, menstrual dysfunction, reduced estrogen exposure, hormonal status. Smoking anti-esterogenic: nutrition, colas replacing milk, inadequate caloric intake, avoidance of milk products, inadequate ca++, vit d, overtraining. Early physical activity provides sustained bone health benefits later in childhood. 1 in 4 women > 50 yrs osteoporosis. 1 in 3 women > 65 vertebral fracture. Significant indirect and direct costs to the health care system. Incidence is rising - number of hip fractures has increased faster than population rate for over 65 years: in 15 years, women over 65 will increase by 30, in 1988, 15000 hip fractures; 28000 expected in the 2018.
