FRSC 1010H Lecture Notes - Lecture 7: The Convicted, Alec Jeffreys, Genotyping

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Deoxyribonucleic acid or dna is a genetic blueprint that makes a living being. It can be extracted from a person"s chromosome. Encodes genetic information for all living organisms. Dna molecule includes sugar backbone, phosphate groups and four nucleotide bases (a, G and c bond together with three hydrogen bonds. A and t bond together with two hydrogen bonds. ~3. 2 billion bp in single copy of human genome. 22 pairs of matched chromosomes and 2 sex chromosomes. Chromosomes in somatic cells are diploid (46 chromosomes total). Gametes (sperm or egg) haploid (23 chromosomes). Coding part of dna (~30,000 genes, ~5% of human genome). Specific region of dna called a locus (plural: loci). Dna mtdna mitochondrial dna (25-1000 copies per cell; ~17,000 bp) maternally inherited. Nuclear dna: 2 copies, 3. 2 billion base pairs per copy. Chromosomes are found in the nucleus of a cell. Stamps on cards used to have to be licked.

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