AN SC376 Lecture Notes - Lecture 12: Animal Welfare, Ibn Zuhr, Cell Culture

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Earliest references to animal experimentation is the greeks in the 2nd and 4th century. Avenzoar is first person to use experimentation on animals and apply it to humans. 1970"s antibiotics and vaccines for leprosy was first tested on armadillos. To protect and ensure safety of people, animals and the environ. Alexis st. martin"s was used to study the physiology of digestion because of his huge wound in his stomach (from a trapping gun) Every year they post data on number of animals and what they are used for in research. Before 2015 mice were used the most, but in 2016 it changed to fish the first. Post the purpose of animals use in research. 5 categories in which the animals are used. Also 5 categories for invasiveness of the experiments. Based on the 3 r"s (replacement, reduction and refinement) Depending on the research we might have to induce disease/toxicity which can cause violation of the 5 freedoms.

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