BIOL107 Lecture Notes - Lecture 5: Prokaryote, Escherichia Coli, Lipopolysaccharide
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Hans gram found that staining with crystal violet distinguished between two kinds of bacteria. Nag and nam form a long chain and have cross linked chains of oligopeptides. Some chains stick out that from links between horizontal lines. Penicillin acts to inhibit bacterial cell wall formation. Cells that don"t have a wall do good in isotonic environments because if it were in a hypotonic / hypertonic area, it would expand/ shrink extensively. Various penicillin antibiotics are produced by fungi. Penicillin binds to an enzyme that catalyses the cross-linking of polypeptides in the peptidoglycan layer. Interferes with the creation of a new cell wall. It binds to a protein (enzyme), it prevents the enzyme from doing its j ob. When bacteria divide, they have to create a new cell, and thus, a new wall has to be created. Penicillin prevents this new creation, so the bacteria won"t have a cell wall and the bacteria cells start exploding.