CHEM263 Lecture Notes - Lecture 10: Laundry Detergent, Prontosil, Umpolung
15 Oct 2016
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Chem 263 - lecture #10 - reaction of side chains of aromatic compounds: alkyl side chain oxidation (see lecture 9 for more examples, clemmensen reaction. Reduction of conjugated ketone to alkyl chain using zn/hg (or sn) amalgam and acid: acetophenone. But why not just do this reaction in one step. You can"t, because when you react the first step, the product is preferred over benzene as the reactant, so it"ll just react again and again, causing polyalkylation (and a big mess), whereas if you did it the. Proper way, benzene is preferred so monoalkylation will just happen. Each group is more electron donating than the last! The clemmensen reaction is much much better. Reviewing tautomerization: tautomers are rapidly interconverting structural isomers **** must know. Fluoroscence digression (may not need to know: fluorescence. Different vibrational and rotational states (within the big one energy state - many little ones: nitro reduction and aromatic amino diazotization reaction, nitro reduction, replacement of n2 of.
