CHEM564 Lecture Notes - Lecture 16: Aptamer, Protein Tag, University Of California, San Francisco
2 May 2017
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Source material: biochemistry: berg, jeremy m. ; tymoczko, john l. ; and stryer, lubert (ncbi bookshelf), molecular cell biology 4th ed. : lodish, harvey; berk, arnold; zipursky, s. lawrence; Matsudaira, paul; baltimore, david; darnell, james e. (ncbi bookshelf): introduction to genetic analysis anthony: j. f. I highly recommend browsing the molecule of the month series at the pdb (http://www. pdb. org/pdb/101/ motm_archive. do: suggested reading: sections 8. 1 to 8. 5 of mikkelsen and cort n, bioanalytical chemistry. A minute to learn, a lifetime to master". Werner arber and hamilton smith in the early 1950"s. Daniel nathans pioneered their use for cutting dna at speci c sequences during the the late 1960s: to biochemists, these exquisitely precise scalpels are marvellous gifts of nature. There isn"t any: restriction enzymes are found in a wide variety of prokaryotes. Their biological role is to cleave foreign dna molecules. The cell"s own dna is not degraded, because the sites recognized by its own restriction enzymes are methylated.
