MMI133 Lecture Notes - Lecture 13: Necrotizing Fasciitis, Vacuole, Macrophage

• School: University of Alberta
• Department: Medical Microbiology and Immunology
• Course: MMI133
• Professor: Judy Gnarpe

Document Summary

Describe at least 3 virulence factors used by bacteria to evade the immune system. Describe at least 3 virulence factors used to enter host cells. Define toxins and provide at least 2 examples. Describe multiple ways bacteria can share virulence factors between them. List some effects viruses can exert on host cells to cause disease. Pathogen: a microorganism that can cause a disease process. Primary pathogens: always cause disease even in healthy immuno-competent individuals e. g. bacillus anthracis. Opportunistic pathogen: a microorganism that may cause right circumstances disease if given the e. g. candida albicans immunosuppression. Pseudomonas aeruginosa burns, cf, hiv, and patients neutropenic cancer. Pathogenicity: capability (of a pathogenic agent) to cause disease. Virulence: degree of pathogenicity of a particular organism. How the pathogen gains entry to the host. Surgical sites and implants can provide a route to bypass these. Some microorganisms have a preferred portal of entry. Only capable of causing disease via a specific route.