NEURO410 Lecture Notes - Lecture 4: Morris Water Navigation Task, Hebbian Theory, Spatial Navigation
Document Summary
Lecture 4: normal aging: cellular correlates of learning and memory (jan 14) Rat: can also use humans; problems = more difficult for longitudinal studies. Normal aging involves changes in appearance and function of the body. Also involves changes in the brain: notably shrinkage. Learning: process by which the enviro/interaction with enviro mods behavioural expression. Process by which knowledge is acquired: more cognitive view. Memory: process by which enviro mods upon behavioural expression (ie learning) = maintained. Process by which knowledge = maintained (in lt) Aging effects on learning and memory: some learning/memory forms = affected in normal aging. Need animal model to study cellular correlates of how aging may influence learning and memory. Outline: cellular correlates: hippocampal dependent learning and memory in rats, hippocampal structure and function, hippocampal synaptic plasticity as model for learning and memory, link b/w hippocampal synaptic plasticity and spatial memory, hippocampal dependent learning and memory in rats.