PHYSL 210 Lecture Notes - Lecture 6: Carotid Body, Blood Gas Tension, Flowchart

• School: University of Alberta
• Department: Physiology
• Course: PHYSL 210
• Professor: Dr. Saswati Das

Document Summary

Peripheral chemo receptor and central in medulla of brain. Mostly in carotid bodies and some in aorta itself. Sensitive indirectly to co2 and directly related to h ions. Most important control of ventilation that we have. Ccrs in our brain located in medulla re directly sensitive to h ions. If you start to get an accumulation of h+ Peripheral : sensitive to large decreases in o2. Body is most sensitive to changes in co2 than oxygen. When pcr re, they re very fast. Requires large decrease in o2 to happen. Hold the o2 level at normal level. Holding alveolar ppo2 to 110 (very close to normal) and changing co2 level. Increasing pco2 and alveolar ventilation goes up as a response. Ventilation reposes change when co2 is held content while changing o2. We start at alveolar po2 at 100. When you reduce it, no change in ventilation till about 60.