PHYSL402 Lecture Notes - Lecture 11: Portal Vein, Vagus Nerve, Parasympathetic Nervous System
13 Oct 2016
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Lecture 11: role of brain in glucose homeostasis (feb. 5/16) Intro (cid:271)rain as a sensor of (cid:271)ody"s nutrient status. Intro brain as a sensor of hormone inputs to regulate glucose homeostasis (in periphery) In response to oral gluc load, are various mech for brain to sense higher glucose levels: taste r signal to nts (part of dorsal complex of hindbrain) Git (are vagal tracts from git and converge on nts) Directly stim brain and stim gut to secrete various peptides (which can enter blood stream and send signal to hindbrain) Recall role of gut in homeo: nerves 2) chemical signal = 2 ways that gut can communicate with hindbrain. Even before reaching liver and cleared, are signals from portal vein that can relay to. Glucose in circulation (first part = portal and mesenteric vein) Nts in hindbrain = known as portal and superior mesenteric portal veins. When glucose lvls drop too much, also sensors in the portal/superior mesenteric portal veins.
