PHYSL402 Lecture 12: L12

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Homeostasis requires relative constancy of total amount and composition of body fluids. Key complications in clinical medicine occur if there are abnormalities in control systems. Fluid intake and output balanced during steady state. Total intake of h2o + electrolyte must match equal output. Note: for the esophagus, vomiting can also occur. Sweating = sensible (we are aware of it, usually) Synthesis: 200ml/day: via normal breakdown of carbs liberates water contributes to water intake (not a conscious intake, though) Insensible: respiratory tract, skin diffusion 700ml/d, skin loss 300-400ml/d (both) Air breathed in = moisturized with water (lose water with breathing) Loss of water via respiration = lost more in dry condition. Skin diffusion not sweating; actual diffusion through skin layer; if pts w/o sweat glands, also experience this loss = separate from sweat glands. If lose protective layer of skin ie burns (may lose up to 5 l can lead to circulatory shock)

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