PHYSL402 Lecture Notes - Lecture 17: Nephron, Renal Pelvis, Distal Convoluted Tubule
7 Nov 2016
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(cid:862)co(cid:374)ti(cid:374)ued(cid:863) (cid:894)march 4/ 16(cid:895) (1) tuft of glomerular capillaries (glomerulus) (2) long tubule to convert of filtered fluid to urine. Up to 1 million nephrons in each kidney. Glomerular capillaries have high hydrostatic p relative to other capillaries (60mmhg) Capillaries covered in epithelial cells entire glo(cid:373)erulus e(cid:374)(cid:272)ased i(cid:374) bo(cid:449)(cid:373)a(cid:374)"s capsule. Filtered fluid (cid:373)o(cid:448)es fro(cid:373) bo(cid:449)(cid:373)a(cid:374)"s (cid:272)apsule throughout the renal tubule. Need excess co to maintain filtration in kidneys (not just remove wastes but also maintains electrolytes) (circled): distal tubule passes in b/w efferent and afferent arteriole. In end, end up with ~400 collecting duct that dumps waste into renal pelvis. Fluid is conditioned as it passes through tubules. Recall: aging: every 10 years after 40 = lose 10% of functional nephrons. Have two main nephrons (depends on where you find them) Regional difference in nephron structure: cortical nephrons with glomeruli in outer cortex short loops of henle. Juxtamedullary nephrons: glomeruli deep in renal cortex next to medulla long loops of.
