PMCOL305 Lecture 16: Lecture 16

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Know the various forms of cocaine and their admin. Know the types of damage it can cause. Was used as anesthetic still is in rare instances, usually eye surgeries. Freud and colleague were some of the first to report its ability to anesthetize by using pins to touch their own corneas; originally meant to treat heroin addiction. Freud recommended it to treat depression and addiction. Used to be part of otc remedies and drinks (coca-cola) Mostly transported in bricks of the powder form. (cid:862)(cid:373)ules(cid:863) (cid:373)ay s(cid:449)allo(cid:449) (cid:373)ultiple (cid:271)ags either tied-off condoms or the fingers of latex gloves. An increasing trend has been smuggling liquid cocaine in carry-on. Grows in highlands of south america shrubs with waxy leaves. Locals chew the leaves mixed with very basic substances (lime to increase extraction) Cocaine = benzoylmethylecgonine; have specific metabolites (ie smoking or with alcohol etc) 500 kg of leaves for 1 kg of paste. Kerosene or gasoline is added to extract active ingredients.

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