PSYCO275 Lecture Notes - Lecture 14: Hebbian Theory, Uch, Retrograde Amnesia
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Where is the memory trace (engram) located? (cid:149) karl lashely (cid:149) studies of the physical location of the engram (in cortex: sensory motor isolation with knife cuts (cid:149) retention and learning unaffected, large and specifically placed lesions (cid:149) mass action memories stored diffusely in brain (cid:149) equipotentiality. Amnesia (cid:149) from greek: a without, mneme memory, (cid:149) the loss, absence, or dysfunction of memory in the absence of other cognitive symptoms. Organic or damage induced (cid:149) ribot, (1882), korsakoff (1887), alzheimer (1907) (cid:149) scoville and milner (1957): h. m. Mnemonic gradient: law of regression (cid:149) loss of memory is inversely related to the time elapsed between the event to be remembered and the injury. Hm: results of mtl removal (cid:149) surgery was effective in reducing seizures (cid:149) no perceptual, motor or cognitive deficits (cid:149) iq increased (cid:149) problem: profound (yet selective) memory deficits (cid:149) global all senses (cid:149) amnestic symptoms: