PSYCO241 Lecture Notes - Lecture 75: Latent Inhibition, Dopaminergic, Cognitive Flexibility

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Frontal pole: abstract maintenance of multiple goals. Default network: daydreaming, mind-wandering, self-relfection/projection, others. Dopamine: reward-seeking , dopaminergic projections to the dlpfc. At the level of motivation, dopamine appears to assign positive value to novelty (panksepp, 1998). At a preconscious level, dopaminergic activity decreases latent inhibition, rendering categories more flexible and allowing more of the complexity of the environment to become salient (peterson et al. , 2002). Finally, at a higher cognitive level, dopamine facilitates the flexible information processing accomplished by the dorsolateral pfc (arnsten & robbins, 2002). Other brain regions helping to generate cognitive flexibility, such as the dorsal anterior cingulate cortex (dacc), may well constitute important additional sources of. The dopaminergic projections from the vta to the frontal lobes innervate dacc as well as pfc, and, as mentioned above, the dacc is sometimes found active during tasks that also activate the dorsolateral pfc (e. g. , duncan et al. , 2000;

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