PSYCO275 Lecture Notes - Lecture 9: Dopamine Agonist, Drug Withdrawal, Drug Tolerance
10 Oct 2016
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Psyco 275 - lecture #9 - psychoactive drugs. Since it has to go through digestive tract though, results are unpredictable. Injection, inhalation and absorption: drugs will have a more direct path to destination, because they do not have to pass through the digestive tract. Intravenously (iv): veins, drug goes directly to brain. This means you can use less of it and get the same result. Also skin (travel directly to the bloodstream) Mechanisms of drug action: drug has to pass through bbb to have effect. Remember, the capillaries in the brain do not have any openings unlike the ones in the periphery: liver terminates most drugs via enzymes. Mechanisms of psychoactive drug action: the general target is the brain, the specific target are the receptors for the drugs in the brain, receptor binding. Effect of drugs proportional to receptor occupancy (the amount of drugs bound = the total magnitude of the effect)
