ANSC 4470 Lecture Notes - Lecture 18: Glut4, Citric Acid Cycle, Glycogen Synthase
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Brown ld, rozance pj, bruce jl, friedman je, hay jr ww and wesolowski sr. 2015. Limited capacity for glucose oxidaion in fetal sheep with intrauterine growth restricion. Am j physiol regul integr comp physiol 309:r920- Will be asked on the quiz (more about metabolism) Where are the authors from: university of colorado anschutz. 3. 36: number of citaions per year per paper, higher the number the beter the journal is, is it inluenial. Prolonged efects, fetal imprining (what happens in utero can afect infant from then on) Insulin dose increases & simulates glucose uptake into cells: response to insulin. If so, where: glucose producion rate is not suppressed by insulin (is supposed to slow down gluconeogenesis) If pyr accoa is inhibited, pyr lactate will occur: reduced glucose oxidaion increases lactate producion. Besides lactate, what substrates could be used for hepaic glucose producion: glycogen breakdown, amino acids, glycerol. In vitro is the opposite, in glass , take issue/cells and study in isolaion.