BIOL 1090 Lecture Notes - Lecture 3: Listeria Monocytogenes, Signal Transduction, Oligosaccharide

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Lecture 3 - sept. 15, 2014: viruses, biological membranes. Non-cellular macromolecular packages that can function and reproduce only within living cells: outside of cells, a virus exists as an inanimate particle (= virion, virion comprised of (encoding a few to hundreds of genes) Viruses bind to a cell surface via specific proteins and enter into cell. This defines the cell types the virus can infect and the host range. Rabies can infect cells in dogs, bats, and humans. Human cold and influenza viruses infect epithelial cells of human respiratory system. Once inside a cell, the virus hijacks cellular machinery to synthesize nucleic acids and proteins: assembles new virus particles. Function of biological membranes: cell boundary , define /enclose compartments, control movement of material into/out of cell , allow response to external stimuli , enable interactions between cells , provide scaffold for biochemical activities ** Mosaic - different particles penetrate the lipid layer.

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