BIOL 1090 Lecture 9: Lecture 9.docx

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Joe Colasanti

Document Summary

Internal ph of 4. 6: h+ atpase, hydrolytic enzymes, acid hydrolases, lysosomal membrane, glycosylated proteins (protects against enzymes, protective lining next to lumen, enzymes in lysosome first made in er then transported to golgi then inserted into autophagic membrane. Function: autophagy (organelle turnover, destruction of organelles, lysosome fuses with er derived autophagic vacuole (cid:224) forms autolysosome, contents enzymatically digested, forms residual body (cid:224) can be released (exocytosis, degradation of internalized material (cid:224) retained (lipfuscin/storage granules, stays within lysosome, plasma membrane components, bacteria (in phagocytic cells) Intracellular digestion: low ph, acid hydrolases, storage, solutes and macromolecules, chemical storage (no excretory system, isolate toxic compounds, sequesters pigments, mechanical support; turgor pressure, gives rigidity to plant supports tissues, stretches cell wall during growth. Cytoskeleton: dynamic network of interconnected filaments and tubules that extends throughout the cytosol (and some organelles) of eukaryotes, functions, structural support, spatial organization within cell, intracellular transport, contractility and motility.