BIOL 1090 Lecture Notes - Lecture 19: Phagocytosis, Cell Membrane, Triskelion

• School: University of Guelph
• Department: Biology
• Course: BIOL 1090
• Professor: Andrew Bendall

Document Summary

Macromolecule transport within, between, and out of cells. Shows how vesicles can have vesicles inside! splat when reach target and gets incoporated into it! If kdel protein escapes --> copi coat = retrograde transport back to er. V-snare (vesicle) & t-snare (target) bind together to dock! After docking --> vesicle fuses with target! Transport proteins from tgn --> other vesicles (after they"ve gone through golgi!) Composed of 3 heavy & 3 light chains. Polyhedral lattice ==> basket-like structure that surrounds vesicle. Ccv adaptor proteins located between lattice & cytosolic face of vesicle. Clathrin coat starts coming in from outside to form vesicle. Structure of clathrin (triskelions) makes curve automatically! Dynamin loops around tubule (tubulase) and pinches vesicle off (pinchase)! Orientation of a protein with respect to the cytoplasm & the interior of the compartments is maintained during/throughout its travels through the endomembrane system!