BIOM 3000 Lecture Notes - Lecture 2: Axon Hillock, Semipermeable Membrane, Extracellular Fluid

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Action potentials: rapid changes in membrane potential of axon, propagation begins @ the axon hillock, propagated over long distance using voltage-gated ion channels, 4 important properties, 1. All-or-none opening of vg sodium channels: 3. Once depolarized, if there is no refractory period, the signal will continue & fire backwards! Let"s say you"re talking to someone, and they say something you hate. The excitatory neuron tells you to slap , vs inhibitory knows that you will probably go to jail. Add them up, decide to hit him that"s the action potential. The axon hillock is the one that is doing the math. If you hit him, go to jail: all or nothing. Action potential: threshold, depolarization, open vg for na, repolarization, open vg for k, hyperpolarization, vg k+ still open, depolarization/hypo-polarization: Note: can"t go higher than +30mv [threshold] because na+ channels quickly close and k+ channels quickly open. So, action potentials all have same amplitude (+30 mv)

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