BIOM 3090 Lecture Notes - Lecture 3: Tears, Transferase, Blood Pressure

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Describe the anatomy and neurochemistry of the autonomic nervous system (ans: 2. Name major receptor subtypes and probably receptor mediated action on effector tissue: 3. Name and predict effects of examples of cholinergic and adrenergic drugs: 4. Identify an unknown drug based on autonomic effects on organ systems: divisions of ans, 1. In general, psns and sns mediate opposing responses in effector organs. Edrf release: nicotinic receptors: nn and nm, nn: found in all ganglia, nm: found on skeletal muscle (somatic nervous system) Contraction: receptor subunits, adrenergic receptors, found in organs innervated by sns and in cns, location and subtype determine the tissue response, alpha receptors (a1, a2, activated by both ne and ep. Increase camp -> more protein kinase -> more phosphorylation: b2 receptors are mostly activated by ep only, ne doesn"t have much of an effect. Tyrosine hydroxylase: converts tyrosine into dopa, 2. Dopa decarboxylase: converts dopa to dopamine, 3.

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