BIOM 3200 Lecture Notes - Lecture 5: Supercooling, Molality, Plasma Osmolality

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Adh and oxytocin are produced in the paraventricular and supraoptic nuclei of the hypothalamus. Adh and oxytocin are stored in and released from the posterior pituitary. Once released into the bloodstream adh promotes resorption of water by the kidneys which releases (cid:858)sti(cid:272)ki(cid:374)ess(cid:859) of (cid:271)lood. Have excessive thirst and very dilute urine. In normal children adh has a circadian rhythm: adh levels increase at night promoting water resorption decreasing the production of urine at night. 2/3 water content is intracellular: 27-30l in cytoplasm. 1/3 extracellular: 11-13 l in interstitial fluid: absorbed through gi tract, 3-3. 5 l in blood plasma: excreted to kidneys, lungs, skin (sweat glands) 3 hours to survive in harsh environment without shelter. Survive without water in desert for several days in hot, dry environment. Solution: lipid is stored in the hump, metabolism od lipid provides significant amount of metabolic water. Turning off thermoregulation is a water conservation process.

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