BIOM 3200 Lecture 4: book notes 4

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Located between the convolutions (coils) of the tubules: within the interstitial tissue are leydig cells, which secrete testosterone. Testosterone is needed for : development and maintenance of the male genitalia (penis and scrotum, male accessory sex organs (prostate, seminal vesicles, epididymides, and vas deferens, development of male secondary sex characteristics. All paracrine/autocrine regulators control gene expression in their target cells to some degree: platelet-derived growth factor, epidermal growth factor, and the insulin-like growth factors that stimulate cell division and proliferation of their target cells. Prostaglandins promote inflammatory process, including the development of pain and fever. Drugs that inhibit prostaglandin synthesis help to alleviate these symptoms: reproductive system. Play a role in ovulation and corpus luteum function in the ovaries and in contraction of the uterus. Excessive production of pge 2 and pgi 2 may be involved in premature labor, endometriosis, dysmenorrhea: digestive system: stomach and intestines produce prostaglandins, inhibit gastric secretions and influence intestinal motility and fluid absorption, respiratory system.

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