CHEM 2700 Lecture Notes - Lecture 3: Sodium Bromide, Old High German, Sodium Chloride
18 Jun 2016
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68 (a) nucleophiles 68 (b) leaving groups 68. 72 (h) effect of solvent in sn2 reactions 72. Iii. 3 sn1 reactions 74 (a) mechanism of sn1 reactions 75 (b) kinetics of sn1 reactions . 75 (c) free energy diagram of sn1 reactions 76 (d) reactivity of the substrates in sn1 reactions . 78 (f) reactivity of the nucleophile in sn1 reactions 78 (g) reactivity of the leaving group in sn1 reactions . 79 (h) effect of solvent in sn1 reactions 80 (i) rearrangement of carbocations 80. Iii. 4 tosylates & mesylates as leaving groups . 81. Iii. 7 e2 eliminations 84 (a) mechanism 84 (b) regiochemistry . Iii. 9 nucleophilic substitutions vs eliminations 88 (a) alkyl halide 88 (b) nucleophile or base . 89 (c) solvent 89 (d) temperature 89 (e) sn2 vs e2 . Nu : a reagent that seeks a positive center e. g. ho , ch3o , h2n , h2o, nh3 (b) leaving groups.
