MBG 1000 Lecture Notes - Lecture 10: Cell Cycle, Dna Replication, Contact Inhibition
6 Apr 2016
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Monday, march 21, 2016 cell cycle control & cancer. They have lost the geneic ability to stop dividing. They are immortal: hela cancer cells are sill growing in a peatree dish from the 1950s, can grow independent of the host if you keep providing them to grow. They show no contact inhibiion: they keep dividing, don"t go into g0. They are de-difereniated cells: stem cells (embryo development) heart cells (this is difereniaion) Cancer cells don"t do this, they go back to something in between the stem cell and the area speciic, b/c of this we cannot predict their patern. Neo-angiogenesis (can simulate the development of new blood vessels into the tumor and provide the tumor with nutrients) Because of the above changes cancer cells are oten called transformed cells. Series of deined stages in the cell"s life cycle. G1 (gap 1): cell performs normal cellular aciviies and can respond to its environment.
