MCB 2050 Lecture 1: MCB2050 Lecture 1: MCB readings : notes W14
10 Dec 2015
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Regulation of gene expression in eukaryotes eukaryotic gene expression can be regulated at the transcriptional, processing or translational level. The fact that they can change continuously is the fact that they have a large array of genes that encode the variant surface glycoproteins (vsg"s) coating these organisms. At any one time only one of these genes are expressed the others are silent. Each change by the trypanosome is a new protein being expressed and this continues until the animal dies from exhaustion. The above is an example of gene regulation, this is done by the vsg"s being temporarily regulated until they are changed again, this is common in eukaryotes. An example is a particular train will be expressed in blood cells but never in nerve cells even though they have the same dna template. Gene expression in eukaryotes involves the transcription of dna into rna and the subsequent translation of that rna into polypeptides.
