MICR 2420 Lecture Notes - Lecture 18: Antibody, Opsonin, Cd47

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TheIuesste:
.ItodutiototheIateIue
sste
Ch..‐.
healthtap.o
iF_LMM
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LikstoalltheUtue/ideolipsaepostedo
CouselikudeIateIueste
folde/odule
iF_LMM
https://.outue.o/ath?=BGJOsioA
~itoathoouo;DaidVette,theBule
ooLiigithoutaiuesste.
https://.outue.o/ath?=GIJKdCWC
IuesstePatI:ashouse
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Weaesuoudedioes;
whyareweotsikoreofte?
xNotalloftheaedisease‐ausigie.
Pathoges
xWehaeaFirstLieofdefee!
xVaiousphsialadheial
aiestohelpuselude&aage
theioes
xWhataeeaplesoftheseaies?
x“o….hathappeshetheaiesae
eahed?
xTheiuessteisalleditopla
x“o..hat istheIuesste?
iF_LMM
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Document Summary

We a(cid:396)e su(cid:396)(cid:396)ou(cid:374)ded (cid:271)(cid:455) (cid:373)i(cid:272)(cid:396)o(cid:271)es; why are we (cid:374)ot si(cid:272)k (cid:373)ore ofte(cid:374)? (cid:120) not all of the(cid:373) a(cid:396)e disease (cid:272)ausi(cid:374)g (cid:894)ie. pathoge(cid:374)s(cid:895) (cid:120) we ha(cid:448)e a(cid:374) first li(cid:374)e of defe(cid:374)(cid:272)e! (cid:120) va(cid:396)ious ph(cid:455)si(cid:272)al a(cid:374)d (cid:272)he(cid:373)i(cid:272)al (cid:271)a(cid:396)(cid:396)ie(cid:396)s to help us e(cid:454)(cid:272)lude & (cid:373)a(cid:374)age the (cid:373)i(cid:272)(cid:396)o(cid:271)es (cid:120) what a(cid:396)e e(cid:454)a(cid:373)ples of these (cid:271)a(cid:396)(cid:396)ie(cid:396)s? (cid:120) o . (cid:449)hat happe(cid:374)s (cid:449)he(cid:374) the (cid:271)a(cid:396)(cid:396)ie(cid:396)s a(cid:396)e (cid:271)(cid:396)ea(cid:272)hed? (cid:120) the i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373) is (cid:272)alled i(cid:374)to pla(cid:455) (cid:120) o(cid:449)hat is the i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373)? (cid:373)i(cid:272)(cid:396)(cid:1006)(cid:1008)(cid:1006)(cid:1004)f(cid:1005)(cid:1011)_lmm. The (cid:373)a(cid:373)(cid:373)alia(cid:374) i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373) has (cid:1006) a(cid:396)(cid:373)s: the i(cid:374)(cid:374)ate s(cid:455)ste(cid:373, the adapti(cid:448)e s(cid:455)ste(cid:373) (cid:373)i(cid:272)(cid:396)(cid:1006)(cid:1008)(cid:1006)(cid:1004)f(cid:1005)(cid:1011)_lmm. I(cid:374)fe(cid:272)tio(cid:374) does (cid:374)ot (cid:374)e(cid:272)essa(cid:396)il(cid:455) (cid:396)esult i(cid:374) disease: if the i(cid:373)(cid:373)u(cid:374)e s(cid:455)ste(cid:373) is effe(cid:272)ti(cid:448)e &/o(cid:396) the (cid:374)u(cid:373)(cid:271)e(cid:396) of i(cid:374)fe(cid:272)ti(cid:374)g o(cid:396)ga(cid:374)is(cid:373)s is s(cid:373)all, the(cid:374) disease (cid:449)ill (cid:374)ot (cid:374)or(cid:373)ally follo(cid:449) i(cid:374)fe(cid:272)tio(cid:374, to (cid:272)ause disease, a pathoge(cid:374) (cid:374)eeds to ha(cid:448)e p(cid:396)ope(cid:396)ties o(cid:396) att(cid:396)i(cid:271)utes it (cid:272)a(cid:374) use to: The(cid:396)e a(cid:396)e (cid:1007) (cid:272)o(cid:373)ple(cid:373)e(cid:374)t a(cid:272)ti(cid:448)atio(cid:374) path(cid:449)a(cid:455)s: the classi(cid:272)al path(cid:449)a(cid:455, the le(cid:272)ti(cid:374) path(cid:449)a(cid:455, the alte(cid:396)(cid:374)ati(cid:448)e path(cid:449)a(cid:455)

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