MICR 2420 Lecture Notes - Lecture 15: Citric Acid Cycle, Benzoic Acid, Bioremediation

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To move & grow,cells need energy that comes from chemical rxns: 1 catabolism = breakdown of complex molecules into smaller ones. Catabolism gives energy for anabolism- but some released as heat. Microbes catalyze many kinds of substrates: polysaccharides disaccharides mono- Sugar (amines & acids) pyruvate fermented or further catabolized to co2 and h2o via tca cycle: lipids and aa glycerol and acetate + other metabolic intermediates, aromatic compounds like lignin and benzoate derivatives acetate through catechol pathway. Partial breakdown of organic food . no electron transfer to inorganic terminal electron acceptor. Complete breakdown of organic molecules with electron transfer to terminal electron acceptor like o2. Use of microbes to detoxify contaminants in the environment- degrade pollutants to nontoxic form exploiting the fact that collectively heterotrophic microbes degrade (oxidize) everything through oxidation =gives energy: or reduction in fermentation or terminal electron acceptors (anaerobic respiration)

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