NUTR 1010 Lecture Notes - Calcitriol, Autoimmune Disease, Osteomalacia
9 Apr 2013
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Document Summary
Metabolic processes: structural support for organs and body segments, protects vital organs, storage reservoir for minerals, production of blood cells in bone marrow, muscle support for movement. 35% organic substances provide strength and flexibility (collagen: a fibrous protein) Minerals form tiny crystals (hydroxyapatite), which cluster around collagen fibers. Minor roles: magnesium, vitamin k, vitamin a, and fluoride. Process of bone remodeling: bone resorption, osteoclasts break down bone, secretes enzymes and acids to erode bone surface, minerals released into blood stream, bone formation, formation of bone by osteoblasts, build collagen matrix. Highest amount attained during the years of normal bone growth. Assessing bone health: dual energy x-ray absorptiometry, measures bone mineral density (bmd, bone mineral content (g)/bone area (cm2) = bmd (g/cm2, monitors changes in bmd, determines risk of osteoporosis, comparison of bmd values, t-score. Compares your bmd to average peak bmd of a 30-year-old healthy adult of similar gender and race. Low bone mass and deterioration of bone tissue.
