NUTR 3070 Lecture Notes - Lecture 7: Adipose Tissue, Nutrient, Glycogen
Document Summary
Nutrition 7 whole body perspective: multiple organs/tissues with specific energy requirements, whole-body handling of macronutrients is in a continuous state of flux. Macronutrient regulation: macronutrient regulation is a multi-issue, short-term macronutrient flux, minutes to hours (ex. between meals, tissue crosstalk, hormones move throughout the body and trigger signalling pathways in their target tissues, ex. Insulin, glucagon, epinephrine etc: usually affects protein function, ex. Phosphorylation of enzymes: long-term macronutrient flux, several hours to days (ex. fasting, starvation, affects gene expression. Hormones: insulin, secretion regulated by gut hormones incretins , hormones that come from the gut, fed state insulin levels. = high: fasted state insulin levels = low, considered an anabolic hormone. Increase fat storage in adipose tissue and fatty acid biosynthesis. Nefa from adipose tissue: fast twitch, used for short duration & contraction ( local glycogen provides energy) Sustained high intensity exercise glucose primary source of energy.