NUTR 3210 Lecture Notes - Lecture 10: Glycogen Phosphorylase, Phosphocreatine, Large Intestine
12 Feb 2017
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Document Summary
Multiple organs/tissues with speci c energy requirements: continuous state of ux. What is the body"s strategy to meet energy requirements (in normal circumstances): carbohydrates. Brain requires 100g/day glycogen stores in liver provide a daily buffer, but not a long- term storage: protein. Lots of protein, but not really stored per se. Proteins have de ned roles (enzymes, structural, etc) Therefore, not typically used as energy source because this would lead to loss of function: fat. Stored in lipid droplets in adipose tissue. Excess lipid storage not good in liver and muscle. What happens in times of starvation? fat utilization spares protein. Short-term macronutrient ux: minutes to hours) i. e. between meals, tissue crosstalk through hormones. Hormones move throughout the boyd and regulate signalling pathways in their target tissues: e. g. insulin, glucagon, epinephrine, etc. Usually affects protein function: e. g. phosphorylation or de-phosphorylation, long-term macronutrient ux. (several hours to days) i. e. fasting, starvation.
