NUTR 3210 Lecture Notes - Lecture 8: Pentose Phosphate Pathway, Acetyl-Coa, Pyruvate Dehydrogenase
4 Oct 2016
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Document Summary
The metabolic fates of glucose: how we use glucose will depend on the energy needs of the cell, glucose is always phosphorylated to glucose 6 phosphate first. Then: g6p can be converted to glucose 1 phophate glycogen (anabolic, g6p can be converted to fructose 6 phosphate (uses pyruvate dehydrogenase) pyruvate acetyl coa. Acetyl coa go through tca and etc for energy production (catabolic) Or it can be used to make fatty acids triglycerides energy stored as fat (anabolic: g6p can be converted to 6-phosphogluconate pentose phosphates (anabolic) hexose monophosphate shunt makes nadph, 5c sugars, ribose. Blood glucose levels start to drop, the pancreas releases glucagon. Glucagon gets broken down into glucose and is released into the blood (by the liver) High blood glucose levels, pancreas secretes insulin. Store excess blood glucose as glycogen (glycogenesis) Glucose is phosphorylated to glucose 6 phosphate (uses 1 atp, hexokinase is catalyst if its in the muscle, if its in the liver its glucokinase)
