NUTR 3210 Lecture Notes - Lecture 22: Glutathione Peroxidase, Hydroperoxyl, Tocopherol
Document Summary
Our vitamins and minerals contribute to 2 types of antioxidant defense. Enzymatic antioxidant defense: minerals or phytochemicals that acy as cofactors within antioxidant enzymes. Vitamin e: fat soluble, widely distributed in foods (fats and oils, in plants, mostly comes from oils, in animals, found in fatty tissues. Not as good a source of plants: in the body, vitamin e acts as an antioxidant, donating a single electron to reduce damaging oxidant molecules, primarily to protect lipid containing membranes from damage to oxidation. Chlymicron returns to the liver as a chylomicron remnant. Alpha tocopherol forms a complex with ttp, which can then enter a. Vldl, which is then circulated around the body to extrahepatic tissue. Vitamin e and lipid peroxidation: main job is protect lipid membrane from free radical damage (particularly hydroxyradical, initiation: unsaturated lipids in the membrane come in contact with hydroxyl radical, which steals a hydrogen from the fa, making water.