NUTR 3210 Lecture Notes - Lecture 12: High-Protein Diet, Oxidative Deamination, Urea Cycle
2 Mar 2017
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3 differences between fasted and fed state: fed state involves formation of both glutamine and alanine. 2: fed state involves excretion of nh3 as urea, whereas the fasted state involves secretion of fed state involves both liver and kidneys ammonium (nh4+) Catabolizing -ketoacid leads to the production of bicarbonate (hco3-: bicarbonate id a weak base that reacts with a h+ (if this happens, no change in ph) High consumption of protein (amino acids) causes a system overload (h= used up) and ph. Tuesday, february 28, 2017 increases a bit 9to ~7. 8) In the fasted state, minor amounts of protein are catabolized (remember that the primary source of energy is fat (tag)) The breakdown of tag causes a production of acidic ketone bodies. So, a fasted state encourages acidosis (ph of around 7. 0-7. 1: also known as ketoacidosis. Products of tag breakdown (long hydrocarbon chains) are not very water soluble so the liver converts these long hydrocarbons into small soluble ketone bodies.
