NUTR 3210 Lecture 13: NUTR*3210 - Lecture 13 (March 2)
3 Mar 2017
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Document Summary
Muscle (or non-hepatic tissue) can become glutamine (fasted/starvation) or becoming glutamine/alanine (fed) and eventually goes to urea can be exerted from kidney or liver. 3 differences between fasted/fed state: fed state involves formation of both glutamine and alanine, fed state involves both liver and kidneys, fed state involves excretion of nh3 as urea, whereas the fasted state involves secretion of ammonium. Catabolizing alpha-ketoacid leads to the production of bicarbonate (hco3-) Bicarbonate is a weak base that reacts with a h+ (if this happens, no change in ph) High consumption of protein (amino acids) cause a system overload (h+ used up) and ph increases a bit to (~7. 8) Active urea cycle in the fed state (in liver) deals with nh3 and hco3- Metabolism of sulfur-containing aa produces a bit of sulphuric acid to deal with. In the fasted state, minor amounts of protein are catabolized (remember primary source of energy is fat [tag])
