NUTR 3210 Lecture Notes - Lecture 13: Heme Oxygenase, Dmt1, Porphyrin
13 Apr 2018
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Iron is found in a lot of different foods at low levels. Rich in liver, meats, and plant sources (e. g. , leafy green vegetables, fruits, nuts) Fe2+- (ferrous: functions of iron in the body include, oxygen transport (i. e. , important for hemoglobin and myoglobin, redox reactions is an active component of the electron transport chain (iron sulfur centers and cytochrome heme proteins) Not necessarily not bad, but can promote radicals (context dependent: iron metalloenzyme (cid:523)enzymes don(cid:495)t function if they don(cid:495)t have iron(cid:524, rda -> 8mg/d men, 18 mg/d women, 27 mg/d pregnancy. Higher for women due to menses /since women lose iron. Higher in pregnant women to cover the needs of the fetus: ul -> 45mg/d (this leads to hemosiderosis) Different forms, different absorption: between 10-18% of the iron ingested is absorbed. How much is absorbed will depend on a person(cid:495)s iron status. /don(cid:495)t want an overload so it(cid:495)s regulated: non-heme iron.
