NUTR 3330 Lecture Notes - Lecture 2: Thiamine Pyrophosphate, Pentose Phosphate Pathway, Pyruvate Dehydrogenase
Document Summary
Structure of thiamin: note the co-enzyme form of thiamin is thiamin pyrophosphate (tpp) What is acetyl coa: central in macronutrient metabolism, carbohydrate, protein and fat all oxidized to acetyl coa, one fate is entrance into critic acid cycle, citric acid cycle is final common pathway for oxidation of macronutrients. Riboflavin (vitamin b2: water soluble, yellow, fluorescent, essential for conversion of vitamin b6 to its co-enzyme forms, coenzyme forms, fmn (flavin mononucleotide) Fad (flavin adenine dinucleotide: primary role of fmn and fad to is transfer hydrogens. Riboflavin (b2): food sources: milk and milk products, photolabile, implications for milk storage, liver, meat, milling of wheat results significant losses, fortified flour in canada. Riboflavin (b2): deficiency: non-specific never fatal, lesion symptoms, cheilosis, magenta tongue, angular stomatitis, seborrheic dermatitis, what other vitamin could riboflavin deficiency affect, vitamin b6 since riboflavin is needed to convert vitamin b6 to its coenzyme form, iron.
