NUTR 3330 Lecture 19: NUTR3330 Lecture 19
Document Summary
Resveratrol: polyphenolic compound described as, 3, 5, 4-trihydroxystilbene, phytoalexin: produced by plants due to stress, plant antibiotic, stillbene compound (class of polyphenols, fat soluble compound that exists in cis and trans for, alglycone or glycoside form. Resveratrol history: used in traditional japanese and chinese medicine in an herbal product called kojo-kon also called. Resveratrol and health: cvd, cancer, longevity - on pharmacological level. Inhibition of reactive oxygen species: resveratrol has direct antioxidant activity, scavenges free radicals, inhibits ldl oxidation, 3. Anti-inflammatory activity: resveratrol can inhibit several inflammatory enzymes including, cycloxygenase, lipoxygenase, resveratrol can inhibit pro-inflammatory transcription factors such as nfkappab, 4. Inhibition of platelet aggregation: platelet aggregation is one of the first steps in formation of a blood clot, therefore related to prevention of a cardiovascular event like myocardial infarction, 5. Inhibition of vascular smooth muscle cell proliferation: related to prevention of the profession of atherosclerosis.
