NUTR 3360 Lecture Notes - Lecture 5: Thrifty Phenotype, Genomic Imprinting, Infant Mortality

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Despite the war, nutrition in the netherlands had generally been adequate up to october 1944. Module 2: part 1 epigenetics and transgenerational effects. By november 26, 1944, official rations, which eventually consisted of little more than bread and potatoes, had fallen below 1000 kcal per day. Widespread starvation was seen especially in the cities of the western netherlands. Food supplies were restored immediately after liberation on may 5, 1945. On the basis of these historical data it is possible to accurately define the beginning and the end of he famine period. The famine affected fertility, weight gain during pregnancy, maternal blood pressure, infant size at birth and central nervous system development. Could study how maternal undernutrition at specific points during gestation affect offspring at birth and throughout life. Examined birth weights of children who had been in the womb at some point during the famine.

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