NUTR 4210 Lecture Notes - Lecture 7: Skeletal Muscle, Blind Experiment, Interval Training

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Improvement in performance with the caffeine: no difference between 3, 6, and 9 mg of caffeine, 3 (cid:373)g (cid:449)as e(cid:374)ough to i(cid:374)du(cid:272)e this effe(cid:272)t, goi(cid:374)g a(cid:271)o(cid:448)e did(cid:374)"t ha(cid:448)e a(cid:374)(cid:455) added effects on performance. Terry graham: concluded little evidence to support the hypothesis that caffeine has ergogenic effects as a result of enhanced fat oxidation and sparing of muscle glycogen use during prolonged aerobic endurance exercise. Is there any truth to this theory: this was the original theory and was studied quite a bit. Idea of responders and non-responders: some participants respond better to the caffeine than others, polymorphism in a particular gene that may make you more susceptible to responding to caffeine than others. Thursday, october 27, 2017: recent evidence points to central nervous system (cns, caffeine crosses all body membranes, including blood-brain barrier; a cns stimulant. How does it work: caffeine is antagonistic to adenosine i. e. caffeine binds to adenosine receptors and prevents typical adenosine effects, antagonistic to adenosine.

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