PSYC 1000 Lecture Notes - Lecture 4: Conditioned Taste Aversion, Sputum, Little Albert Experiment

• School: University of Guelph
• Department: Psychology
• Course: PSYC 1000
• Professor: Dan Meegan

Document Summary

Mutations not differentially affected by natural selection. Mutations that conferred a reproductive advantage to all. Autosomes: 22 pairs, same in m and f. English family half suffer from a speech & language disorder. Compare affected to unaffected speech repetition esp. multi-syllabic non-words (e. g. , sastelgint) Why non-words? orofacial motor control open mouth wide & stick out tongue language grammar problems structural/functional brain abnormalities . Structural mri: minor reduction of gray matter in 3 areas involved in motor control and speech. Genome scan of affected and unaffected ke family members pointed to a broad locus on chromosome 7. Unrelated person with similar disorder break in chromosome 7 in middle of ke locus break disrupted gene foxp2. Foxp2 is a transcription factor that regulates gene expression during brain development (esp. motor control centres) Foxp2 different than in non-echolocation bats knockouts have reduced vocalizations. Dna extracted from bones (cave in spain)