PSYC 2410 Lecture Notes - Lecture 8: Nerve Growth Factor, Brain-Derived Neurotrophic Factor, Neurotrophin

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Embryonic development postnatal-childhood development then in adulthood a stable fixed organ. The cns continues to change throughout our entire life brain plasticity. Embryonic development postnatal/childhood development in adulthood a plastic organ. Throughout: genes environment e. g. environment in utero, postnatal experiences. After formation cells need to: differentiate (e. g. muscle cells, liver cells, neurons, glia) Key steps of cellular differentiation: totipotent: early embryonic cells (fertilized egg), can differentiate in any cell type in the body, pluripotent: initial differentiation. Stem cells: 2 properties: unlimited divisions without differentiation, potential to differentiate into different cell types. Three layers of embryonic cells: ectoderm. Outermost of the 3 layers: mesoderm. Referred to as an organizer: endoderm. Three components: neural plate folds to form neural groove, lips of neural groove fuse to form the neural tube + central canal + neural crest . Induction: mesoderm neural plate: neural proliferation. After the closure of the neural tube.

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