ZOO 3000 Lecture Notes - Lecture 2: Stratified Squamous Epithelium, Motility, Hemidesmosome
11 Oct 2017
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1) tight or occluding junctions (zo) contain several transmembrane proteins: occludin, claudin, jam intercellular diffusion barrier to water establishes functional domains in plasma a) za: 2) anchoring junctions: two types, za and ma. *****missed rest of slide***** b) anchoring junctions: ma or desmosomes cadherins desmocollin and desmoglein attach to intermediate filaments by attachment plaques (desmoplakins-plakoglobins) cytoskeleton of cells calcium triggers cadherin zipper binding. Mechanical stability and force dissipation by linking. 1) structural attachment between epithelium and connective tissue: anchored by hemidesmosomes and focal adhesions (cell-to-emc anchoring junctions) basal lamina separates ******* ionic charge in the basal lamina plays a role in kidney ultrafiltration. 4) regulation and signalling: influences epithelial cell shape, proliferation, differentiation, motility during development, and regeneration. 5) tissue scaffolding: basal lamina guides new cells or processes during regeneration classification of epithelia composed of cells three basic types. Width, depth, and height are approximately equal. 2. the different types of ***** typical exam question:
